The purpose of this study is to investigate the effects of adult male circumcision on premature ejaculation (pe). Therefore, between december 2009 and march 2014, a total of 575 circumcised men and 623 uncircumcised men (control group) were evaluated. There is much less recorded research material on how circumcision can help treat erectile dysfunction, premature ejaculation, low libido problem absence of sexual desire, orgasm difficulties and dyspareunia. Erectile dysfunction or male sexual dysfunction has been considered as a neuro-biological problem or a psychological disturbance. A recent study discovered that premature ejaculation is five times more likely when adjusted for erectile dysfunction and circumcision. Moreover, in israel- a country that routinely circumcises their baby boys for religious reasons- viagra is so common there that the pfizer pharmaceutical company asked for permission to market viagra without a doctors prescription- making it an over-the. The human foreskin is highly innervated, 5 21 29 and vascularized 29 sensitive erogenous tissue. 6 29 it plays an important role in normal human sexual response and is necessary for normal copulatory behavior. 40 an understanding of this role is now emerging in the scientific literature. Removal of the foreskin (circumcision) interferes with normal sexual function. To reiterate, circumcision does not clinically prove to be a treatment option to cure premature ejaculation. To ensure appropriate assessment and treatment, premature ejaculation having multi factorial determinants, needs to be understood as individualized male sexual dysfunction. international journal of impotence research (2020) circumcision does not have effect on premature ejaculation a systematic review and meta-analysis y.