Is a reticulocyte a mature erythrocyte? Wiki user 012642. Pronormoblast, early normoblast, intermediate normoblast, late normoblast, reticulocyte and erythrocyte. To accurately measure reticulocyte counts, automated counters use a combination of laser excitation, detectors and a fluorescent dye that marks rna and dna (such as titan yellow or polymethine). Reticulocytes can be distinguished from other circulating cells because they emit a signal that is neither strong (like lymphocytes) nor weak (like red blood cells). Reticulocyte r-tiku-lo-st a young erythrocyte showing a basophilic reticulum under vital staining. Reticulocyte (re-tiky-l-st), a young red blood cell containing a basophilic cytoplasmic network precipitated by brilliant cresyl blue representing residual polyribosomes such cells become more numerous during the process of. A reticulocyte that leaves the bone marrow and circulates for a day or so until it loses its rrna and becomes a mature red blood cell, or erythrocyte. A stain or dye which will cause the rna of the reticulocyte to be. An immature form of an erythrocyte, called a reticulocytes, is released into circulation. Step five after one to two days, the reticulocyte becomes a mature erythrocyte. Reticulocyte is the beginning of what would be a red cell if it matures. Reticulin fibrosis is a condition in which some of the immature red cells are not maturing appropriately. What does a reticulocyte have to do to become an erythrocyte. The bone marrow and circulates for a day or so until it loses its rrna and becomes a mature red blood cell, or erythrocyte. To reduce the chance that a staining artifact would result in misclassifying a mature erythrocyte as a punctate reticulocyte when using a reticulocyte stain, the cell in question should have two or more discrete blue granules that are visible without requiring fine focus adjustment.